Latex agglutination test for fecal occult blood.

Rapid immunochemical detection of fecal occult blood by use of a latex-agglutination test.

A novel immunochemical test, "Hemolex," is characterized and compared with three guaiac tests: "Hemoccult" (Smith-Kline, U.S.A.), "Hemofec" (Boehringer Mannheim, F.R.G.), and "Fecatwin Sensitive" (Labsystems, Finland). We tested 191 stool specimens from patients, 144 from healthy persons. The sensitivity of Hemolex was 0.6 mL of blood per 100 g of stool. It reacts with neither animal hemoglobin...

NCD for Fecal Occult Blood Test

False Negative Fecal Occult Blood Test: Prozone Effect

Dear editor, the fecal occult blood test is the presently widely used screening laboratory test for colorectal cancer. At present, the test is usually based on an immunological diagnostic principle (1, 2). A false positive fecal occult blood is common and widely mentioned in literature. Nevertheless, the false negative is little mentioned in the paper. Here, the authors discuss the issue of the...

unochemical Fecal Occult Blood Test–Positive Individuals

Downlo kground: We aimed to define the potential of the fecal DNA assay as an alternative or in addition to rrently used immunochemical fecal occult blood test (iFOBT) for the early diagnosis of colorectal . thods: A total of 560 individuals aged 50 to 69 years with a positive iFOBT were recruited from an FOBT regional screening program. Twenty-six were diagnosed with adenocarcinoma, 264 with i...

A latex agglutination test for lectin binding.

Blood group A + H substance purified from hog gastric mucin was fixed to polystyrene particles by physical absorption to produce a lectin-agglutinable latex. Agglutination of this latex by soybean agglutinin, concanavalin A, and wheat germ agglutinin is specifically inhibited by the respective monosaccharide haptens and is not affected by known noninhibitory sugars. The sensitivity of the assay...